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Clinical studies

Through research and trials, we’ve developed a clear understanding of the numerous positive effects Herstat has as a cold sore treatment and in providing relief for those who suffer from recurring cold sore outbreaks (or, as they are also known, fever blisters). Focused studies on the benefits of Herstat’s ingredients, including the natural substance propolis, has provided clinical results which offer positive supporting data.

How Herstat compares to other products

Data from major published studies on other products show that most of them help to heal cold sores about half a day to one day faster than a placebo or without any treatment.

The most recent study published on Herstat cold sore treatment showed that Herstat sped up healing so successfully that people involved in the trial were rid of symptoms an average of 3.5 days faster than if they had been treated using the placebo.

Herstat's participants, on average, were completely free of all symptoms at day six of the study. Without treatment, fever blisters will typically take ten to twelve days to heal.

More information about this trial

This trial was double-blind, meaning that the participants – and the individuals dispensing the product to be used during the clinical study – were not aware of whether they were handling Herstat ointment or the placebo.

This is a well-known study design used to eliminate any intentional or unintentional bias which might affect the results of a study.

Sixty-eight people were used in the trial: thirty-five were randomly given a placebo and thirty-three were provided with Herstat.

Participants were asked to apply their treatment five times daily and fill out a cold sore research diary in which they could note down the stage their symptoms had reached, as well as how much pain they were experiencing.

Using this information time to healing was monitored, as well as time to loss of pain. On average, all individuals using Herstat had normal skin within 6.24 days and reported being pain free by day seven. These results support the efficacy of Propolis ACF, the purified propolis extract used in Herstat, suggesting that it can help accelerate the healing process and relieve symptoms a lot faster than no treatment.

In contrast, those using the placebo had to wait 9.77 days before their skin returned to normal, whilst 22.9% of them were still complaining of pain on day seven.

What did participants think of the product?

Before it was revealed to them whether they had been using Herstat ointment or the placebo, those involved in the study were asked for their opinion of the treatment.Their responses give a glowing evaluation of Herstat's power and show how successful Propolis ACF is in the treatment of fever blisters.

Those who had been using Herstat's cold sore ointment were happy with the results; 18.2% stated it was "somewhat effective", whilst 81.8% stated it was "very effective".

In the placebo group, however, only 5.7% said that the product was "very effective", 11.4% said it was "somewhat effective", and the remainder thought the placebo was either "hardly effective" or "ineffective".

When asked whether they would use the product again, 93.9% of the people who had been using Herstat during the clinical trial said "yes". In comparison, the reverse was true for the placebo group, as 94.3% said they would not use the product again.

Considering the prevalence of fever blisters among the global population, the above responses should be extremely encouraging to sufferers of the virus everywhere.

Success in earlier trials

Another earlier study conducted by Professor Zenn Sosnowski, whose research is responsible for the production of Herstat's active ingredient Propolis ACF, showed similar positive results. This was another double-blind study that separated participants into a treatment group and a placebo group. The results showed that the treatment group saw a drastic drop in healing time of their lesions. The mean healing time for the treatment group's previous fever blister outbreaks was 10.9 days, which was cut to just 4.1 days when using Propolis ACF. Meanwhile, the placebo group experienced only a slightly shorter healing time on average, dropping from a mean of 9.8 days to 8.4 days.

Try Herstat, the clinically proven treatment for fever blisters

If you would like to see and feel the results for yourself, we have two products available.

Firstly there is our Herstat ointment, which helps to speed healing and reduce swelling. It also helps to diminish the pain and discomfort you might experience during an outbreak.

The second product is our Herstat LipCare stick, which you can use in between outbreaks for everyday protection – and is also great for defending yourself against UVA / UVB as well as avoiding dry or chapped lips.